Glycosyl compounds
![Apexbio Technology LLC MHC class II antigen (45-57) [Homo sapiens] 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096667.png-250.jpg)
Apexbio Technology LLC MHC class II antigen (45-57) [Homo sapiens] 1mg
MHC class II antigen 45-57 is a synthetic peptide derived from human major histocompatibility complex class II molecules It is designed to facilitate studies on antigen presentation by MHC class II molecules which bind extracellularly derived peptide antigens and present them to CD4 helper T lymphocytes thereby initiating adaptive immune responses MHC class II antigen 45-57 exerts its biological activity primarily by serving as a model antigenic peptide for investigating MHC II-mediated antigen presentation and T-cell activation Based on these properties MHC class II antigen 45-57 holds research potential in studies of MHC II-mediated immune responses T-cell activation and the cellular immune mechanisms involved in pathogen defense and autoimmune diseases
eMolecules 77-86-1 | Tris Base | Oakwood Chemicals | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 2.5kg | 480169728
Tris Base | Oakwood Chemicals | 77-86-1 | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 2.5kg | 480169728
Medchemexpress LLC α,α-trehalose 6-phosphate potassium | 136632-28-5 | MFCD00133871 | 99.0% | 498.46 g/mol | C12H21K2O14P | 5 MG
α,α-trehalose 6-phosphate potassium is the potassium salt of trehalose 6-phosphate supplied as a high-purity research reagent for biochemical and metabolic studies. It is suitable for in vitro assays, analytical standards, and metabolite research, and is provided in small, accurately weighed quantities for reproducible results.
- High purity (99.0%) for reliable experimental outcomes.
- Available in small sizes (including 5 mg) for analytical and method development work.
- Molecular weight 498.46 g/mol; molecular formula C12H21K2O14P.
- Potassium salt form compatible with common aqueous buffers.
- Intended for research use only and supplied with SDS and COA documentation.
Medchemexpress LLC Complement Factor D/ 50ug | 50ug
Complement factor D also known as Adipsin plays a crucial role in the alternative pathway of the complement system and when complexed with factor C3b it cleaves factor B This cleavage activates the C3bbb complex converting it to the C3 convertase of the alternative pathway Complement Factor D/Adipsin Protein Human (HEK293 His Solution) is the recombinant human-derived Complement Factor D/Adipsin protein expressed by HEK293 with C-10 His labeled tag
Medchemexpress LLC D-α-Hydroxyglutaric acid | 13095-47-1 | 98.0% | 148.11 | 1 ML
D-α-Hydroxyglutaric acid is the primary metabolite that accumulates in the neurometabolic disorder D-2-hydroxyglutaric aciduria. It acts as a weak competitive antagonist of α-ketoglutarate (α-KG), inhibiting multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. This compound increases reactive oxygen species (ROS) production, binds to and inhibits ATP synthase, and suppresses mTOR signaling. It also accumulates in human cancers with neomorphic mutations in IDH1 and IDH2 genes.
- Weak competitive antagonist of α-ketoglutarate (α-KG).
- Inhibits multiple α-KG-dependent dioxygenases.
- Increases reactive oxygen species (ROS) production.
- Binds to and inhibits ATP synthase.
- Suppresses mTOR signaling.
- Accumulates in human cancers with IDH1 and IDH2 gene mutations.
Alkali Scientific D (+) Raffinose Pentahydrate, 500 G
D (+) Raffinose Pentahydrate is a high-quality carbohydrate reagent used in laboratory experiments that require a pure and stable form of raffinose. This pentahydrate version contains 500g of the substance, ensuring sufficient quantity for a wide range of applications. Raffinose is a trisaccharide composed of galactose, glucose, and fructose, often used in scientific studies related to plant biology, fermentation processes, and biochemistry. The high purity and pentahydrate form make it ideal for precise laboratory work. This chemical is often used in enzyme assays, sugar analysis, and osmotic pressure studies. The substance is available in a 500g package, with the product sourced from Alkali Scientific.
Medchemexpress LLC Pulsatilla saponin D | 68027-15-6 | 913.10 | 1 ML
Pulsatilla saponin D (SB365), also known as Hederacolchiside A, is a natural product isolated from the root of Pulsatilla chinensis. It is an anti-tumor agent.
- Shows apoptotic effect.
- Strongly inhibits c-Met expression in gastric cancer cells.
- Suppresses the growth and proliferation of 5 human pancreatic cancer cell lines.
- Exhibits anti-angiogenic activity.
- Shows anti-tumor activity in NSCLC cancer cells.
- Demonstrates anti-tumor activity in a Lewis lung carcinoma model.
Medchemexpress LLC 2-O-α-D-Glucopyranosyl-L-ascorbic Acid | 129499-78-1 | 100 MG
2-O-α-D-Glucopyranosyl-L-ascorbic Acid is an orally active glucoside derivative of ascorbic acid that can be hydrolyzed by α-glucosidase to release ascorbic acid. It is used in research related to tumors, inflammation, and other conditions.
- Inhibits melanin synthesis
- Prevents UV-induced cell damage
- Promotes collagen synthesis in skin fibroblasts
- Induces oxidative stress to inhibit tumor growth
![Medchemexpress LLC N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] | 1597403-47-8 | MFCD27952932 | 99.5% | 451.34 g/mol | C22H24Cl2N2O4 | 10MM 1ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235622.png-250.jpg)
Medchemexpress LLC N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] | 1597403-47-8 | MFCD27952932 | 99.5% | 451.34 g/mol | C22H24Cl2N2O4 | 10MM 1ML
ISRIB (trans-isomer) is a small-molecule inhibitor of the integrated stress response that potently inhibits PERK and reverses eIF2α phosphorylation. It is supplied as a 10 mM solution in DMSO or as solid quantities for use in biochemical and cellular assays; reported purity is 99.49% and molecular weight 451.34 g/mol.
- Potent PERK inhibition with reported IC50 of 5 nM.
- Reverses eIF2α phosphorylation in cellular assays.
- Available as 10 mM solution in DMSO and multiple solid sizes.
- High purity suitable for research applications.
- Molecular weight 451.34 g/mol and formula C22H24Cl2N2O4.
- Useful for biochemical and cell-based studies of the integrated stress response.
Medchemexpress LLC D-Tetrahydropalmatine | 3520-14-7 | MFCD11046348 | 355.43 | 1 ML
D-Tetrahydropalmatine is an isoquinoline alkaloid primarily found in the genus Corydalis. It acts as a dopamine (DA) receptor antagonist, showing preferential affinity for D1 receptors. Additionally, it is identified as a potent inhibitor of organic cation transporter 1 (OCT1).
- Dopamine receptor antagonist
- Preferential affinity toward the D1 receptors
- Potent organic cation transporter 1 (OCT1) inhibitor
- Purity: 99.84%
- Appearance: Solid
- Color: White to light yellow
- Initial source: Plants Papaveraceae Corydalis yanhusuo W. T. Wang
Medchemexpress LLC D-N-Acetylgalactosamine | 1811-31-0 | MFCD00135832 | 97.0% | 221.21 | 1 ML
D-N-Acetylgalactosamine is an endogenous metabolite. It is a cell surface glycosylation residue that participates in cell-cell/cell-matrix interaction as a recognition site for cell surface receptors. It binds to the asialoglycoprotein receptor (ASGPR) on hepatocytes via the terminal glycosylated protein, affecting the interaction between apoptotic extracellular vesicles (apoEVs) and ASGPR, blocking the internalization of apoEVs, and thereby blocking the regulatory effect of apoEVs on the liver, affecting liver homeostasis and regeneration.
- Endogenous metabolite
- Cell surface glycosylation residue
- Participates in cell-cell/cell-matrix interaction as a recognition site for cell surface receptors
- Binds to asialoglycoprotein receptor (ASGPR) on hepatocytes
Medchemexpress LLC Complement Factor D/ 50ug | 50ug
Complement Factor D/Adipsin Protein cleaves factor B in complex with factor C3b activating the C3bbb complex to form the C3 convertase in the alternate pathway analogous to C1s in the classical pathway Complement Factor D/Adipsin Protein Mouse (HEK293 Fc) is the recombinant mouse-derived Complement Factor D/Adipsin protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Tau-D/0N4R Human 1 500ug
Recombinant human Tau-D/0N4R is a 133-amino-acid fragment of microtubule-associated protein tau supplied with a C-terminal 6xHis tag. Expressed in E. coli and provided lyophilized from PBS with 1 mM PMSF, the product is >95% pure by reducing SDS-PAGE and is suitable for biochemical, biophysical, and assay development studies related to tau function and aggregation.
- Contains 133 amino acids with a C-terminal 6xHis tag.
- Expressed in E. coli for consistent recombinant production.
- Greater than 95% purity as determined by reducing SDS-PAGE.
- Lyophilized from PBS with 1 mM PMSF for stability.
- Stable refrigerated short term or frozen for long-term storage.
- Not recommended to reconstitute below 100 μg/mL in ddH2O.
Medchemexpress LLC Schisantherin D | 64917-82-4 | 5 MG
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of *Schisandra sphenanthera*. It demonstrates anti-HIV replication activities with an EC50 of 0.5 μg/mL. Additionally, Schisantherin D inhibits endothelin receptor B (ETBR) and exhibits hepatoprotective effects.
- Dibenzocyclooctadiene lignan
- Isolated from the fruit of *Schisandra sphenanthera*
- Demonstrates anti-HIV replication activities
- Inhibits endothelin receptor B (ETBR)
- Exhibits hepatoprotective effects